Why Vapor Pressure?
Vapor pressure measurement is the best method of determining osmolality, and the thermodynamic limitations of vapor pressure osmometry are least restrictive. For these reasons, vapor pressure osmometry is superior for most fluids in biology and medicine in which water is the solvent.
The vapor pressure method determines osmolality at room temperature with the sample in natural equilibrium. This precludes cryoscopic artifacts due to high viscosity, suspended particles, or other conditions that can interfere with freezing point determinations, giving Vapro a much broader range of error-free applications